Thursday, September 29, 2011

Negative Feedback Loops...Bad for us?

Simply the negative feedback loop is an occurrence, wether positive or negative, that will change the current stable levels but will ultimately end right back at homeostasis. For example, blood sugar will increase with the amount of sweets eaten, but after a certain period of time the blood sugar will return to its stable level that it has always been at.

The reason for the return to homeostasis is due to insulin and glucagon. If there is a spike in glucose in the blood then the pancreas receptors will release more insulin and targets the liver. The liver will then store the glucose as glycogen for later use. If there is a decrease in glucose the pancreas receptors release glucagon and tells the liver to use the glycogen stored, and turn it into glucose.  The chart above shows Dr. Rood's blood glucose level rising as he ate the snickers and drank the can of sprite. His blood glucose spiked but his body's natural response was to release insulin to control the extra glucose and store it in the liver for later use and returned his blood glucose level back to normal which was 104 mg/dL. It was an interesting experiment watching him prick himself and continuously check his blood levels haha.

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